Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic / sediment

Using Bio-concentration Factor module Bio-concentration Factor of the test chemical was estimated to be 5973, 5972, 5970, 5942 and 5680 at pH range 1-10, 11, 12, 13 and 14, respectively. These value exceed the bio concentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulate in the aquatic organisms.

Additional information

Bioaccumulation: aquatic / sediment

Various predicted data of the test chemical were reviewed for the bioaccumulation end point which are summarized as below:

 

In a prediction done by using Bio-concentration Factor module (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017)), Bio-concentration Factor of the test chemical was estimated to be 5973, 5972, 5970, 5942 and 5680 at pH range 1-10, 11, 12, 13 and 14, respectively. These value exceed the bio concentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulate in the aquatic organisms.

 

Another predicted data was estimated using SciFinder database (American Chemical Society (ACS), 2017) for predicting the bioconcentration factor (BCF) of test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 6420 at pH range 1-10 respectively (at 25 deg C) which exceeds the bio concentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulative in the food chain.

 

On the basis of above results for test chemical, it can be concluded that the BCF value of test substance was evaluated to be ranges from 5680 to 6420, which exceeds the bioconcentration threshold of 5000, indicating that the test chemical is expected to be very bioaccumulative in the food chain.