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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
other information
Study period:
1995
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 471 (Bacterial Reverse Mutation Assay)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of assay:
bacterial gene mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
O,O,O-tris(4-nitrophenyl) thiophosphate
EC Number:
264-697-5
EC Name:
O,O,O-tris(4-nitrophenyl) thiophosphate
Cas Number:
64131-85-7
Molecular formula:
C18H12N3O9PS
IUPAC Name:
O,O,O-tris(4-nitrophenyl) phosphorothioate

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
other: non-mutaganic

Therefore, Nitro RF was considered to be non-mutaganic without
and with S9 mix in the plate incorporation as well as in
the preincubation modification of the Salmonella/microsome test.