Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Standard health hazard book, recommended in the ECHA guidance on REACH endpoints of May 2008

Data source

Reference
Reference Type:
review article or handbook
Title:
Sax's Dangerous Properties on Industrial Materials
Author:
Lewis R.J.
Year:
1996
Bibliographic source:
9th ed. Volumes 1-3. p. 2519. Van Nostrand Reinhold: New York, NY (USA), 1996

Materials and methods

Test guideline
Guideline:
other: guideline not specified
Principles of method if other than guideline:
Standard health hazard book that is recommended in the ECHA Endpoint Specific Guidance R7a, of May 2008.
Test type:
other: not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
10 800 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Remarks:
Migrated information
Conclusions:
The following LD50 value for Octanoic acid, methyl ester is taken from standard health hazard book, recommended in the ECHA guidance on REACH endpoints of May 2008.
LD50 (oral, rat) = 10800 mg/kg bw