Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
Batch No LQC 0701302
Purity 98.1%

Study design

Analytical monitoring:
yes
Duration of testopen allclose all
Duration:
6 d
pH:
4
Initial conc. measured:
4.122 mg/L
Duration:
6 d
pH:
7
Initial conc. measured:
4.989 mg/L
Duration:
6 d
pH:
9
Initial conc. measured:
3.847 mg/L

Results and discussion

Preliminary study:
In the incubated samples at pH 4, 7 and 9 no significant reduction of the test item concentration was observed. After the incubation time of 6 days the test item concentration were determined to be higher than 90% of the initial concentrations.
Test performance:
As a consequence of the results of the pre-tests, no further testing was necessary at any pH values.
Transformation products:
no
Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
25 °C
DT50:
> 1 yr
pH:
7
Temp.:
25 °C
DT50:
> 1 yr
pH:
9
Temp.:
25 °C
DT50:
> 1 yr

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Therefore, it can be estimated that the half-time of GR-86-3794 is higher than one year at 25.0°C at all pH values tested.