Registration Dossier

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 1974
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
other: Inhouse SOP (method A.11) validated by Ciba which is comparable to standard OECD guideline 203.
Deviations:
not specified
Principles of method if other than guideline:
In house SOP (method A.11) validated by Ciba which is comparable to standard OECD guideline 203.
GLP compliance:
no
Analytical monitoring:
no
Details on sampling:
No data
Vehicle:
not specified
Test organisms (species):
other: Fish (Trout)
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Post exposure observation period:
No data
Hardness:
No data
Test temperature:
14 °C
pH:
7.4 - 8
Dissolved oxygen:
No data
Salinity:
No data
Nominal and measured concentrations:
100, 200 and 1000 mg/l
Details on test conditions:
No data
Reference substance (positive control):
not specified
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Conclusions:
LC50 for FAT 40062/A in Trout is found to be >1000 mg/l.
Executive summary:

Acute fish toxicity study with FAT 40062/A was carried out in trout fish according to in house SOP (method A.11) validated by Ciba which is comparable to standard OECD guideline 203. Total 8 trout fishes were used per concentration. The pH was between 7.4 to 8. Three concentrations 100, 200 and 1000 mg/l were used in this study. After 48 h, all the fishes were survived in all the three test concentrations used in the study. No mortality was found in the study up to highest concentration of 1000 mg/l. So, based on the study results, LC50 for FAT 40062/A in fish is >1000 mg/l.

Description of key information

Acute fish toxicity study with FAT 40062/A was carried out in trout fish according to inhouse SOP (method A.11) validated by Ciba which is comparable to standard OECD guideline 203. Total 8 trouts were used per concentration. The pH was between 7.4 to 8. Three concentrations 100, 200 and 1000 mg/l were used in this study. After 48 h, all the fishes were survived in all the three test concentrations used in the study. No mortality was found in the study up to highest concentration of 1000 mg/l. So, based on the study results, LC50for FAT 40062/A in Trout fish is > 1000 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information