Registration Dossier
Registration Dossier
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EC number: 619-447-3 | CAS number: 99607-70-2
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysis of cloquintocet was determined according to the principles of OECD 111. Cloquintocet behaves as expected for an ester. In strongly alkaline solution de-esterification is very rapid, slower at slightly alkaline pH and very slow in the range of pH 5 to 7. The free acid (i.e. [(5-chloroquinolin-8-yl)oxy]acetic acid; CAS#: 88349-88-6; company code CGA153433) was the sole hydrolysis product found in the experiment and is therefore considered to be hydrolytically stable.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 133 d
- at the temperature of:
- 20 °C
Additional information
In hydrolysis studies cloquintocet behaves as expected for an ester. In strongly alkaline solution de-esterification is very rapid, slower at slightly alkaline pH and very slow in the range of pH 5 to 7. The following half-lives at 20°C were found (concentration of the test substance 0.4 mg/L). pH 1 = 29.8 days, pH 5 = 4.4 years, pH 7 = 133.7 days, pH 9 = 6.6 days and pH 13 = <5 minutes (25°C). The free acid (i.e. [(5-chloroquinolin-8-yl)oxy]acetic acid; CAS#: 88349-88-6; company code CGA153433) was the sole hydrolysis product found in these experiments, therefore the transformation product can be considered as hydrolytically stable.
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