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Based on the results of a GLP study performed according to the OECD 301B guideline, 4-methyl-3-thiosemicarbazide is not readily biodegradable.

 

In accordance with column 2 of REACH Annex IX, the biodegradation in soil and/or sediments study (required in section 9.2.1.3) does not need to be conducted as the substance can be expected to have a low potential for adsorption based on its intrinsic properties (log Kow is a negative value).