Registration Dossier
Registration Dossier
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EC number: 939-651-9 | CAS number: 1474044-70-6
Endpoint summary
Administrative data
Description of key information
Additional information
Only acute toxicity data for aquatic organisms are available for SDIBP. One acute daphnia study and one algae study were conducted for SDIPB to determine the toxicity of test substance to aquatic organisms. The read-across acute fish study of sodium xylene sulphonate (CAS No 1300-72-7) data was used for acute toxicity to fish, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5. The study was conducted in 1993 following the US EPA Guideline - EPA-OTS 5797.1400 - Fish Acute Toxicity Test (Collins, 1993). Rainbow trout were exposed to the test substance for 96 hours in freshwater under static conditions. The nominal 96-hour LC50 was greater than the highest test concentration, 1000 mg/L. No deaths or abnormal behavior were observed in the test at any of the 5 concentrations. Exposure of Pseudokirchneriella subcapitata to the SDIBP following the OECD 201 under GLP gave ErC50 values of greater than 100 mg notifiable substance (ns). The 72 hours NOEC was 100 mg ns/L (Huntsman, 2012f).
The acute toxicity of the SDIBP to the freshwater invertebrate Daphnia magna has also been investigated in a GLP compliant study and gave a 48-hour EC50 of greater than 100 mg ns/L based on mobility (Huntsman, 2012g).
There are no microbial toxicity studies for the SDIBP. The read-across respiration inhibition study of sodium cumene sulphonate (CAS No 28348-53 -0) is applied to support SDIBP (Fiebig, 2009). The study followed OECD Guideline 209 was carried out under static conditions with the limit concentration 1000 mg active substance (a.i.) /L, corresponding to 2500 mg test item/L. No inhibition was observed based on respiration rate. The 3-hour EC10 was 1000 mg/L active substance (nominal), which was the only concentration tested.
The summary of acute aquatic toxicity data for SDIBP:
For fish: 96-h LC50 to Oncorhynchus mykiss= 1000 mg/kg (similar to EPA OTS 97.1400; read-across from sodium xylenesulphonate)
For invertebrates: 48-h EC50 to Daphnia magna, immobilization = 100 mg/L (OECD 202).
For algae: 72-h ErC50 to the Pseudokirchneriella subcapitata, growth rate = 100 mg/L (OECD 201).
For microorganism: 3h EC10 to the activated sludge, respiration inhibition= 1000 mg/L(OECD 209; read-across from sodium cumenesulphonate).
Chronic aquatic toxicity data for SDIBP:
For algae:72-h NOEC to the Pseudokirchneriella subcapitata, growth rate = 100 mg/L (OECD 201).
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