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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
review article or handbook
Title:
Dose doc no : D399
Author:
RSC Publishing
Year:
2011
Bibliographic source:
Dictionary of Substances and their effects (DOSE):-Arnold, J. M. et al Chemosphere 1990, 21(1-2), 183-191.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
DOSE database
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3,4-xylidine
EC Number:
202-437-4
EC Name:
3,4-xylidine
Cas Number:
95-64-7
Molecular formula:
C8H11N
IUPAC Name:
3,4-dimethylaniline

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Tetrahymena pyriformis

Study design

Test type:
not specified
Water media type:
not specified
Limit test:
yes
Total exposure duration:
48 h

Test conditions

Reference substance (positive control):
not specified

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
234 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Toxicity to microorganism (Tetrahymena pyriformis) (48h) examined at dose concentration 234 mg/l.