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EC number: 200-353-2 | CAS number: 57-88-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Monitoring data
Administrative data
- Endpoint:
- monitoring data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Well documented publication. The study was intended to report on the detailed fatty acid and sterol composition of raw and treated sewages from different treatment plants. The publication gives important information on cholesterol contents in influent and effluent of actual sewage treatment plants.
Data source
Reference
- Reference Type:
- publication
- Title:
- Fatty acids and sterols in domestic wastewaters
- Author:
- Quemeneur, M. and Marty, Y.
- Bibliographic source:
- Wat. Res. Vol.28, No5, pp.1217-1226, 1994
Materials and methods
- Principles of method if other than guideline:
- Raw and treated sewage from physical-chemical and biological wasterwater treatment plants were analyzed for fatty acids and sterols by HPLC and GC.
Test material
- Reference substance name:
- Cholesterol
- EC Number:
- 200-353-2
- EC Name:
- Cholesterol
- Cas Number:
- 57-88-5
- Molecular formula:
- C27H46O
- IUPAC Name:
- cholest-5-en-3-ol
Constituent 1
Results and discussion
- Details on results:
- - Characterization of the raw sewage showed that most (80 -95%) of the fatty acids and sterols were in the particulate fraction. Cholesterol represented 23 -38% of the particulate sterols. In the dissolved fraction of the raw sewage, the percentage of cholesterol was 42 -62%.
- The lipid composition of raw sewage is dominated by four fatty acids: 18:1 (n-9), 16:0, 18:0 and 18:2 (n-6) and two sterols: coprostanol and cholesterol.
- The investigations in the three plants showed that raw sewage constitutes a daily input of 4 -8 g of fatty acids and 0.5 -0.6 g of sterols per capita. For treated wastewaters, the values range from 0.2 to 4 g of fatty acids and from 0.01 to 0.2 g of sterols per capita.
Applicant's summary and conclusion
- Conclusions:
- Based on the fact that most sterols (80-95%) are in the particulate fraction and cholesterol constitutes between 23 and 38% of the particulate sterols, the daily input in raw sewage of 0.5-0.6 g of sterols per capita can be recalculated to a daily input of approximately 0.09-0.22 g cholesterol per capita.
Together with the amount of cholesterol in the soluble fraction of raw sewage, the daily input in raw sewage of 0.5-0.6 g of sterols per capita constitutes between 0.1 and 0.3 g cholesterol.
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