Registration Dossier
Registration Dossier
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EC number: 224-339-0 | CAS number: 4316-74-9
Endpoint summary
Administrative data
Description of key information
The estimated toxicity values of sodium N-methyltaurinate were calculated by EPI Suite, ECOSAR v1.11. For fish, the lowest estimated LC50 (96 h) is 440 g/L, the experimentally determined LC50 (96 h) is 1702 mg/L according to the guideline study (OECD 203) on Danio rerio.
For daphnids, the lowest estimated EC50 (48 h) is 29.69 g/L. Experimental studies have not been done for sodium N-methyltaurinate. An empirical EC50 value for Americamysis bahia is published by Patoczka et al. for the read-across substance methyl oleoyl taurate (12.8 mg/L), which was determined according to the New Jersey Administrative Code, 7:18.
For green algae, the lowest estimated EC50 (96 h) is 75.54 g/L. Experimental studies are only available for the read-across substance sodium N-methyl oleoyl taurinate. This empirical study is a guideline study according to OECD 201 using Desmodesmus subspicatus. According to the study, the NOEC is 6.8 mg/L and the ErC50 (72 h and 96 h) is 106.4 mg/L and 77.7 mg/L, respectively.
The empirically determined toxicity values for invertebrates and algae of the read-across substances are lower than the calculated values by EPI Suite. Nevertheless, both, the empirical data and the estimations are rather high, so that the studies on the read-across substance support the results of the EPI Suite estimation.
Both, the empirical toxicity values of the read-across substances and the calculated toxicity values for sodium N-methyltaurinate indicate LC50/EC50 values of > 1 mg/L for fish, invertebrates and green algae. In addition, the studies on biodegradability show that the substance sodium N-methyltaurinate is readily biodegradable. Hence, we conclude that sodium N-methyltaurinate does not have to be classified for environmental toxicity.
Additional information
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