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Short-term toxicity to fish

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Description of key information

No toxic effects to fish up to the limit of water solubility (< 0.05 mg/L).

Key value for chemical safety assessment

Additional information

The acute toxicity of 2-ethyl-2-[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl bisheptanoate (CAS 78-16-0) to fish was investigated in a study following OECD guideline 203. Rainbow trout (Oncorhynchus mykiss, reported as Salmo gairdneri) were used as test organisms (Comber, 1991). The fish were exposed to the test substance in a semi-static test system. The study was conducted as a limit test with an exposure time of 96 hours. At test termination a LC50 >1000 mg/L based on nominal test substance concentrations was determined.
Thus toxic effects on fish are not expected up to the water solubility limit of the substance (< 0.05 mg/L).
As it can be seen in the data matrix of the category justification in section 13 and the overall endpoint summary, IUCLID 6.1, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results within the polyol esters category, i.e. no toxic effects to aquatic organisms were observed up to the limit of water solubility.