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EC number: 700-483-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species, other
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: model considered reliable by OECD
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSAR R.6, May 2008
- Principles of method if other than guideline:
- The Bioconcentration Factor (BCF) was determined by calculation. This calculation was performed by the computer program from US-EPA (EPIWIN software BCFBAF v3.00)
- GLP compliance:
- no
- Remarks:
- not applicable (QSAR calculation)
Test material
- Reference substance name:
- Diallyl 2,2'-oxydiethyl dicarbonate
- EC Number:
- 205-528-7
- EC Name:
- Diallyl 2,2'-oxydiethyl dicarbonate
- Cas Number:
- 142-22-3
- Molecular formula:
- C12H18O7
- IUPAC Name:
- diallyl 2,2'-oxydiethyl dicarbonate
Constituent 1
- Radiolabelling:
- no
Test organisms
- Test organisms (species):
- other: Fish, species not specified
Study design
- Route of exposure:
- aqueous
- Test type:
- other: QSAR calculation
- Water / sediment media type:
- natural water: freshwater
Test conditions
- Reference substance (positive control):
- no
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- 4.843 L/kg
- Basis:
- whole body w.w.
- Calculation basis:
- other: QSAR calculation
- Details on results:
- Using the regression-based estimate (traditional method) of the computer program BCFBAF from US-EPA a Bioconcentration Factor (BCF) of 4.843 L/kg wet-wt was calculated.
Any other information on results incl. tables
Using the regression-based estimate (traditional method) of the computer program BCFBAF from US-EPA a Bioconcentration Factor (BCF) of 4.84 L/kg wet-wt was calculated for the active substance Diallyl-2,2'-oxydiethyl dicarbonate. Using the Arnot-Gobas method, which is based on mechanistic first principles, an aquatic BCF of 4.627 L/kg wet-wt is the result.
The whole body primary biotransformation rate estimate for fish results in a half-life of 0.08888 days, whereby the bio half-life is normalized to 10 g fish at 15 °C. The rate constant (kM) for 10 g fish is 7.799/day. This is taken into account to predict the apparent metabolism half-life in fish of Diallyl-2,2'-oxydiethyl dicarbonate. With the Arnot-Gobas method it is possible to differentiate between three trophic levels. For the lower trophic level the BCF results in 2.771 L/kg wet-wt, for a mid trophic level the result is 2.963 L/kg wet-wt and for the higher trophic level 3.6 L/kg wet-wt.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- BCF = 4.843
- Executive summary:
The Bioconcentration Factor (BCF) was determined for 'diallyl 2,2'oxydiethyl dicarbonate" by calculation. This calculation was performed by the computer program from US-EPA (EPIWIN software BCFBAF v3.00). Estimation: BCF = 4.843
Since the multi-constituent to be registered (EC 700-483-4) contains as main ingredient 'diallyl 2,2'oxydiethyl dicarbonate', the experimental data from this substance were used in a read-across approach.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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