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Short-term toxicity to aquatic invertebrates

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Description of key information

- LC50 (48h) = 18 mg/L for freshwater invertebrates [guideline equivalent or similar to EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)] 
- LC50 (96h) = 70.7 mg/L for marine water invertebrates [test followed internal procedures of the laboratory (Static acute Mysid shrimps toxicity test, June 1982)]

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
18 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
70.7 mg/L

Additional information

Since RAV 7NG contains as main ingredient 'diallyl 2,2'oxydiethyl dicarbonate', the experimental data from this substance were used in a read-across approach.

Justification for read-across from supporting substance RAV 7AT (diallyl 2,2'-oxydiethyl dicarbonate; CAS 142-22-3; EC 205-528-7): about 70 % of RAV 7NG (EC 700-483-4) consists of components that can be found in the commercial ADC grades known as RAV 7AT, Nouryset 200 and CR39. Merely from comparing the similar production processes of these two substances it is apparent that RAV 7AT and RAV 7NG are closely related to each other.  Finally, the physical-chemical, toxicological and ecotoxicological properties of RAV 7NG and RAV 7AT are almost equal and as a result, read across is justified.

This endpoint is filled from data from one study in Daphnia magna (Suprenant et al., 1982) and another in Mysidopsis bahia (mysid shrimp) (Ward, 1982a). The 48-hour EC50 value for 'diallyl 2,2'-oxydiethyl dicarbonate' in Daphnia magna is 18 mg/L and the 96-hour EC50 value in Mysidopsis bahia is 70.7 mg/L.

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