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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Hazardous Substances Data Bank (CCOHS)

Data source

Referenceopen allclose all

Reference Type:
other: Authoritative data base
Title:
HSDB Number : 6321
Year:
2011
Bibliographic source:
HSDB (Hazardous Substances Data Bank); Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington DC: Amer Chem Soc pp. 5-4, 5-10 (1990)
Reference Type:
other: Authoritative data base
Title:
HSDB Number : 6321
Year:
2011
Bibliographic source:
HSDB (Hazardous Substances Data Bank); Meylan WM, Howard PH; J Pharm Sci 84: 83-92 (1995)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Calculated using Log Kow
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Trichloroacetyl chloride
EC Number:
200-926-7
EC Name:
Trichloroacetyl chloride
Cas Number:
76-02-8
Molecular formula:
C2Cl4O
IUPAC Name:
trichloroacetyl chloride
Radiolabelling:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: fish

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3
Calculation basis:
other: Calculated value using Log Kow
Remarks on result:
other: Kow : 0.88

Applicant's summary and conclusion

Conclusions:
A BCF of 3 was calculated for trichloroacetyl chloride, using an estimated log Kow of 0.88 and a recommended regression-derived equation. This BCF value suggests that trichloroacetyl chloride will not bioconcentrate in aquatic organisms and therefore there will be no bio-accumulation in aquatic organisms
Executive summary:

A BCF of 3 was calculated for trichloroacetyl chloride, using an estimated log Kow of 0.88 and a recommended regression-derived equation. This BCF value suggests that trichloroacetyl chloride will not bioconcentrate in aquatic organisms and therefore there will be no bio-accumulation in aquatic organisms

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