Registration Dossier
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EC number: 263-174-9 | CAS number: 61791-42-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Pursuant to ECHA decision CCH-D-2114394004-54-01/F (issued 22 March 2018) a sub-acute oral repeated dose toxicity study (combined repeated dose toxicity study with the reproduction/developmental toxicity screening test) according to OECD guideline 422 and a sub-chronic oral repeated dose toxicity study (90-day) according to OECD guideline 408 are currently being performed. Based on the results of the sub-acute and sub-chronic toxicity studies (28 and 90 days), the hazard assessment with respect to repeated dose toxicity will be updated.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Link to relevant study records
- Endpoint:
- short-term repeated dose toxicity: oral
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Endpoint:
- sub-chronic toxicity: oral
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- no study available (further information necessary)
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
No data on repeated dose toxicity with the registered substance are available. Pursuant to ECHA decision CCH-D-2114394004-54-01/F (issued 22 March 2018) a sub-acute oral repeated dose toxicity study (combined repeated dose toxicity study with the reproduction/developmental toxicity screening test) according to OECD guideline 422 and a sub-chronic oral repeated dose toxicity study (90-day) according to OECD guideline 408 are currently being performed.
The hazard assessment of Ethanesulfonic acid, 2 -(methylamino)-, N-coco acyl derivs., sodium salts with respect to repeated dose toxicity will be updated in due course when the results of the studies are available.
Justification for classification or non-classification
No data on repeated dose toxicity with the registered substance are available but a sub-acute oral repeated dose toxicity study according to OECD guideline 422 and a sub-chronic oral repeated dose toxicity study (90-days) according to OECD guideline 408 are currently ongoing. The data currently available provide not sufficient evidence that would imply a classification for repeated dose toxicity according to the CLP Regulation (EC) No. 1272/2008 and are therefore conclusive but not sufficient for classification. However, since appropriate studies with repeated administration are currently ongoing, the overall conclusion for classification and labelling regarding repeated dose toxicity needs to be re-assessed once reliable study results are available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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