Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
Deviations:
not specified
GLP compliance:
no
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Div. Lab. Vers.
- Expiration date of the lot/batch: 11/2003

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Solubility and stability of the test substance in the solvent/vehicle: <2 g/l [in water]
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Details on inoculum:
Sludge: 100 mg/L suspended solids
Waste water plant: ARA-PRO RHENO Basel communal
Duration of test (contact time):
28 d
Initial conc.:
30 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
O2 consumption
Details on study design:
ThOD: 2.42 mg O2/mg
Concentration: 30 mg/L test substance in test medium
Reference substance:
other: yes (but name was not cited in the study report)
Parameter:
% degradation (test mat. analysis)
Value:
0
Sampling time:
28 d
Remarks on result:
other: Std deviation not specified
Parameter:
BOD5
Value:
0 mg O2/g test mat.
Results with reference substance:
Biodegradation of the reference substance after 14 d = 84 %
Validity criteria fulfilled:
yes
Interpretation of results:
not inherently biodegradable
Conclusions:
The test substance was not considered to be inherently biodegradable.
Executive summary:

A study was performed to assess the inherent biodegradability of the test substance FAT 93450/A (of ca. 96 % purity) in an aerobic aqueous medium according to OECD Guideline 302 C.

The mean value of the biodegradation of test substance after 28 d was 0 %. Hence, FAT 93450/A can be considered to be not inherently biodegradable.

The biochemical oxygen demand (BOD5) after 5 d was 0 mg O2/g. Comparing this with the COD of FAT 93450/A of 2018 mg O2/g, the BOD5/COD ratio is 0. Hence, FAT 93450/A can also be considered to be not readily biodegradable.

Description of key information

FAT 93450/A is neither readily nor inherently biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed
Type of water:
freshwater

Additional information

An inherent biodegradation study with FAT 93450/A (of ca. 96 % purity) was performed in an aerobic aqueous medium according to OECD Guideline 302C. The mean value of the biodegradation of test substance after 28 d was 0 %, while the reference substance after 14 d was biodegraded as 84 %. The biochemical oxygen demand (BOD5) after 5 d was 0 mg O2/g. The COD of FAT 93450/A was found to be 2018 mg O2/g in a study conducted according to DIN 38409 -H 41. Since the BOD5 after 5 days was zero, the BOD5/COD quotient is mathematically not defined. Under the study conditions, the test substance was not considered to be neither readily nor inherently biodegradable.