1,8-bis(phenylthio)anthraquinone

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1999

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Principles of method if other than guideline:

48 h screening test with 20 daphnids per dose level.

GLP compliance:

not specified

Specific details on test material used for the study:

Test material: FAT 93450/A

Analytical monitoring:

no

Vehicle:

not specified

Test organisms (species):

Daphnia magna

Details on test organisms:

no data

Test type:

not specified

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Hardness:

not specified

Test temperature:

Start: 19 °C; end: 21 °C

pH:

Start: 7.9; end: 7.9

Dissolved oxygen:

Start: 98 %; end: 97 %

Nominal and measured concentrations:

Nominal: 100 mg/L

Reference substance (positive control):

no

Duration:

48 h

Dose descriptor:

EC0

Effect conc.:

100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Duration:

48 h

Dose descriptor:

EC100

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality

Validity criteria fulfilled:

yes

Conclusions:

The EC0 for Daphnia magna was determined to be 100 mg/L (i.e. ca. 96 mg a.i./L). The EC50 and EC100 were both >100 mg/L (i.e. ca. >96 mg a.i./L).

Executive summary:

A study was conducted to evaluate the acute toxicity of the test substance (at ca. 96 % purity) to Daphnia magna. Groups of 20 daphnids were exposed at 0, 0.39, 1.56, 6.3, 25 or 100 mg/L for 48 h.

No significant effects were seen on mobility throughout the study. Sedimentation of the test substance was observed as of 6.3 mg/L. The EC0 was determined to be 100 mg/L (i.e. ca. 96 mg a.i./L). The EC50 and EC100 were both >100 mg/L (i.e. ca. >96 mg a.i./L).

Description of key information

A study was conducted to evaluate the acute toxicity of the test substance (at ca. 96 % purity) to Daphnia magna. Groups of 20 daphnids were exposed at 0, 0.39, 1.56, 6.3, 25 or 100 mg/L for 48 h. No significant effects were seen on mobility throughout the study. Sedimentation of the test substance was observed as of 6.3 mg/L. The EC0 was determined to be 100 mg/L (i.e. ca. 96 mg a.i./L). The EC50 and EC100 were both > 100 mg/L (i.e. ca. >96 mg a.i./L).

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Effect concentration:

96 mg/L