Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 412-300-2 | CAS number: 139504-68-0 AMBER CORE
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A key study evaluating the short-term toxicity of Amber Core (P-#620) to rainbow trout (Oncorhynchus mykiss) is available. The 96h-LC50 was determined to be 4.1 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.1 mg/L
Additional information
One key study according to the OECD Guideline 203, EEC Annex V Part C.1 (84/449/EEC) and with GLP standards is available on the rainbow trout (Oncorhynchus mykiss). Groups of ten juvenile fish were exposed to a range of five concentrations of Amber Core (P-#620) dispersed in water: 1.0, 1.8, 3.2, 5.6 and 10 mg/L, plus one control and one solvent control. Observations were made on the numbers of dead fish and the incidence of sub-lethal effects after 3, 6, 24, 48, 72 and 96 hours exposure. The 96h-LC50 and the highest concentration with no mortality (NOEC) were determined to be 4.1 mg/L (95% confidence limits: 3.3-5.0 mg/L) and 1.8 mg/L respectively. The results are expressed in terms of measured concentration. Measured concentrations ranged from 80 to 144% of nominal at 0 hours, 92 to 109% of nominal at 24 hours and 100 to 102% of nominal at 96 hours (average 104%).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
