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Guidance on Safe Use

Guidance on Safe Use

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First-aid measures

1.Description of first aid measures
Immediately remove contaminated clothing. If the patient is likely to become unconscious, place and transport in stable sideways position (recovery position). First aid personnel should pay attention to their own safety.

If inhaled:
If difficulties occur after dust has been inhaled, remove to fresh air and seek medical attention.

On skin contact:
Immediately wash thoroughly with soap and water, seek medical attention.

On contact with eyes:
Wash affected eyes for at least 15 minutes under running water with eyelids held open.

On ingestion:
Rinse mouth immediately and then drink plenty of water, induce vomiting, seek medical attention.


2. Most important symptoms and effects, both acute and delayed
Symptoms: The most important known symptoms and effects are described in the following:

Information on toxicological effects

Acute toxicity

Assessment of acute toxicity:
Virtually nontoxic after a single ingestion. Virtually nontoxic after a single skin contact. Virtually nontoxic by inhalation. The product has not been fully tested. The statements have been derived in parts from products of a similar structure or composition.

Experimental/calculated data:
LD50 rat (oral): > 5,000 mg/kg (OECD Guideline 401)
No mortality was observed.

LC50 rat (by inhalation): > 5.9 mg/l 4 h
The product has not been tested. The statement has been derived from substances/products of a similar structure or composition. Tested as dust aerosol.

LD50 rat (dermal): > 2,000 mg/kg (OECD Guideline 402)

Irritation

Assessment of irritating effects:
Not irritating to the skin. Not irritating to the eyes.


Experimental/calculated data:
Skin corrosion/irritation rabbit: non-irritant (OECD Guideline 404)

Serious eye damage/irritation rabbit: non-irritant (OECD Guideline 405)

Respiratory/Skin sensitization

Assessment of sensitization:
Skin sensitizing effects were not observed in animal studies.

Experimental/calculated data:
Buehler test guinea pig: Non-sensitizing. (OECD Guideline 406)

Guinea pig maximization test guinea pig: Non-sensitizing. (similar to OECD guideline 406)

Germ cell mutagenicity

Assessment of mutagenicity:
The substance was mutagenic in various bacterial test systems; however, a mutagenic effect could not be confirmed in mammalian cell culture. The substance was not mutagenic in a test with mammals.

Carcinogenicity

Assessment of carcinogenicity:
No data available.

Reproductive toxicity

Assessment of reproduction toxicity:
The potential to impair fertility cannot be excluded when given at maternally toxic doses. The results were determined in a Screening test (OECD 421/422).

Developmental toxicity

Assessment of teratogenicity:
The results of animal studies gave indication of a developmental toxic/teratogenic effects with high doses. The results were determined in a Screening test (OECD 421/422).

Specific target organ toxicity (single exposure)

Assessment of STOT single:
Based on the available information there is no specific target organ toxicity to be expected after a single exposure.


Repeated dose toxicity and Specific target organ toxicity (repeated exposure)

Assessment of repeated dose toxicity:
Repeated uptake leads to changes in clinico-chemical/hematological parameters.

and

Classification of the substance or mixture

According to Regulation (EC) No 1272/2008 [CLP]

Repr. 1B (unborn child)
Aquatic Chronic 2

H360D, H411

For the classifications not written out in full in this section the full text can be found in section 16.


2.2. Label elements

According to Regulation (EC) No 1272/2008 [CLP]

Pictogram:


Signal Word:
Danger

Hazard Statement:
H360D May damage the unborn child.
H411 Toxic to aquatic life with long lasting effects.

Precautionary Statements (Prevention):
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.

Precautionary Statements (Response):
P308 + P311 IF exposed or concerned: Call a POISON CENTER or doctor/physician.
P391 Collect spillage.

Precautionary Statements (Storage):
P405 Store locked up.

Precautionary Statements (Disposal):
P501 Dispose of contents/container to hazardous or special waste collection point.


According to Regulation (EC) No 1272/2008 [CLP]

Labeling of special preparations (GHS):
Only for professional users. EUH208: May produce an allergic reaction. Contains: 2-NAPHTHOL

According to Regulation (EC) No 1272/2008 [CLP]

Hazard determining component(s) for labelling: C.I.SOLVENT BLACK 29



Further important symptoms and effects are so far not known.


3. Indication of any immediate medical attention and special treatment needed
Treatment: Treat according to symptoms (decontamination, vital functions), no known specific antidote.

Fire-fighting measures

1.Extinguishing media
Suitable extinguishing media:
dry powder, foam

Unsuitable extinguishing media for safety reasons:
carbon dioxide

Additional information:
Avoid whirling up the material/product because of the danger of dust explosion.

2. Special hazards arising from the substance or mixture
harmful vapours
Evolution of fumes/fog. The substances/groups of substances mentioned can be released in case of fire.

3. Advice for fire-fighters
Special protective equipment:
Wear a self-contained breathing apparatus.

Further information:
The degree of risk is governed by the burning substance and the fire conditions. Contaminated extinguishing water must be disposed of in accordance with official regulations.

Accidental release measures

1.Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Use personal protective clothing.

2. Environmental precautions
Contain contaminated water/firefighting water. Do not discharge into drains/surface waters/groundwater.

3. Methods and material for containment and cleaning up
For small amounts: Pick up with suitable appliance and dispose of.
For large amounts: Contain with dust binding material and dispose of.
Avoid raising dust.

Handling and storage

1. Precautions for safe handling
Breathing must be protected when large quantities are decanted without local exhaust ventilation.

Protection against fire and explosion:
Avoid dust formation. Take precautionary measures against static discharges.

2. Conditions for safe storage, including any incompatibilities
Further information on storage conditions: Keep container tightly closed and dry; store in a cool place.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

1. Control parameters

Components with occupational exposure limits


135-19-3: 2-naphthol
117527-94-3: reaction mass of: tert-alkyl(C12-C14)ammonium bis[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphthalenolato(2-)]-chromate(1-); tert-alkyl(C 12-C14)ammonium bis[1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphthalenolato(2-)]-chromate(1-); tert-alkyl(C12-C14)ammonium bis[1-[[5-(1,1 -dimethylpropyl)-2-hydroxy-3-nitrophenyl] azo]-2-naphthalenolato(2-)]-chromate(1-); tert-alkyl(C12-C14)ammonium [[1-[(2-hydroxy-5-ni trophenyl)azo]-2-naphthalenolato(2-)]-[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphthalenolato(2-)]]-chromate(1-); tert-alkyl(C12-C14)amm onium [[1-[[5-(1,1-dimethylpropyl)-2-hydroxy-3-nitrophenyl] azo]-2-naphthalenolato(2-)]-[1-[(2-hydroxy-5-nitrophenyl)azo]-2-naphthal enolato(2-)]]-chromate(1-); tert-alkyl(C12-C14)ammonium ((1-(4(or 5)-nitro-2-oxidophenylazo)-2-naphtholato)(1-(3-nitro-2-oxido-5-pen tylphenylazo)-2-naphtholato))chromate(1-)

PNEC
freshwater: 0.1 mg/l

sediment (freshwater): 0.54 mg/kg

marine water: 0.01 mg/l

sediment (marine water): 0.054 mg/kg

STP: 1 mg/l


DNEL
worker:
Inhalation: 0.94 mg/m3

worker:
dermal: 0.13 mg/kg

consumer:
Inhalation: 0.23 mg/m3

consumer:
dermal: 0.07 mg/kg

consumer:
oral: 0.07 mg/kg


2. Exposure controls
Personal protective equipment
Respiratory protection:
Suitable respiratory protection for lower concentrations or short-term effect: Particle filter with high efficiency for solid and liquid particles (e.g. EN 143 or 149, Type P3 or FFP3).

Hand protection:
Chemical resistant protective gloves (EN 374)
Suitable materials also with prolonged, direct contact (Recommended: Protective index 6, corresponding > 480 minutes of permeation time according to EN 374):
e.g. nitrile rubber (0.4 mm), chloroprene rubber (0.5 mm), polyvinylchloride (0.7 mm) and other
Supplementary note: The specifications are based on tests, literature data and information of glove manufacturers or are derived from similar substances by analogy. Due to many conditions (e.g. temperature) it must be considered, that the practical usage of a chemical-protective glove in practice may be much shorter than the permeation time determined through testing.
Manufacturer's directions for use should be observed because of great diversity of types.

Eye protection:
Safety glasses with side-shields (frame goggles) (e.g. EN 166)

General safety and hygiene measures
Handle in accordance with good industrial hygiene and safety practice.

Stability and reactivity

1. Reactivity
No hazardous reactions if stored and handled as prescribed/indicated.


Corrosion to metals:
Corrosive effects to metal are not anticipated.
Formation of flammable gases: Remarks: Forms no flammable gases in the presence of water.


2. Chemical stability
The product is stable if stored and handled as prescribed/indicated.

3. Possibility of hazardous reactions
Dust explosion hazard.


4. Conditions to avoid
Avoid dust formation. Avoid deposition of dust. Avoid sources of ignition. Avoid humidity.

5. Incompatible materials

Substances to avoid:
strong oxidizing agents, strong bases, strong acids

6. Hazardous decomposition products

Possible decomposition products:
carbon oxides, nitrogen oxides, chromium oxides, toxic gases/vapours

Disposal considerations

Waste treatment methods

Must be disposed of or incinerated in accordance with local regulations.


Contaminated packaging:
Uncontaminated packaging can be re-used.
Packs that cannot be cleaned should be disposed of in the same manner as the contents.