Registration Dossier
Registration Dossier
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EC number: 640-964-5 | CAS number: 218451-68-4
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Reaction products of coconut oil with polyethyleneglycol and 2-ethyl-2-(hydroxymethyl)propane-1,3-diol
- EC Number:
- 640-964-5
- Cas Number:
- 218451-68-4
- Molecular formula:
- not applicable because UVCB
- IUPAC Name:
- Reaction products of coconut oil with polyethyleneglycol and 2-ethyl-2-(hydroxymethyl)propane-1,3-diol
- Details on test material:
- - Name of test material (as cited in study report): Marlowet 4753
- Physical state: cloudy white suspension with a viscosity similar to corn oil
- Lot/batch No.: S94505, Date Nov.19, 1999
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubility
- Medium:
- n-octanol
- Solubility:
- > 800 g/L
- Temp.:
- 21 °C
- Test substance stable:
- yes
- Details on results:
- After mixing, the contents of the test tubes were clear homogeneous (single phase) solutions.
These results were consistent with octanol and test substance being miscible liquids at 21 °C.
Applicant's summary and conclusion
- Conclusions:
- The solubility of Coconut oil, reaction products with polyethylene glycol and trimethylolpropane in n-octanol was greater than 0.80 g/mL at 21 °C (< 800 g/L).
- Executive summary:
The solubility of Coconut oil, reaction products with polyethylene glycol and trimethylolpropane in n-Octanol was tested according the preliminary test as indicated in OECD guideline 116 for the determination of fat solubility.
The solubility of Coconut oil, reaction products with polyethylene glycol and trimethylolpropane in n-octanol was greater than 0.80 g/mL at 21 °C (< 800 g/L).
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