Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 1990
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: According to OECD Guideline 202 and GLP Standard.
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1990
Report Date:
1990

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
Phase I
Qualifier:
according to
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
Principles of method if other than guideline:
Not applicable.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
Name for report: P0087
Batch-No.: TK 1-19.9.89
Purity: 99.7 %
Solubility in water 120 g/L

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
356 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
In an acute toxicity study on invertebrates (Daphnia magna) the 48 hour EC50 was determined to be 356 mg/L.
Executive summary:

A static acute toxicity test with Daphnia magna was performed in year 1990 according to OECD Guideline 202 and GLP.

No immobilisation or effects on the Daphnia were noted neither after 24 h nor after 48 h. The pH of the test solutions (8.1), the oxygen concentrations and temperature of the test solutions were within acceptable limits (Oxygen concentration: 80 - 100 % saturation, temperature: 20.8 - 21.9 °C).

The 48 hour EC50 was determined to be 356 mg/L.