Registration Dossier
Registration Dossier
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EC number: 202-179-2 | CAS number: 92-69-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Additional information
As p-PP is an intermediate only occupational exposure may occur and this is limited by the use of RMMs and PPE to prevent dermal exposure as it has been shown to be a skin irritant and sensitiser. No significant inhalation exposure occurs due to low vapour pressure. Therefore, conduct of animal studies to investigate reproduction toxicity are scientifically unjustifiable.
Justification for selection of Effect on fertility via oral route:
Study not scientifically justified due to lack of human exposure.
Effects on developmental toxicity
Description of key information
As p-PP is an intermediate only occupational exposure may occur and this is limited by the use of RMMs and PPE to prevent dermal exposure as it has been shown to be a skin irritant and sensitiser. No significant inhalation exposure occurs due to low vapour pressure. Therefore, conduct of animal studies to investigate develpmental toxicity are scientifically unjustifiable.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Additional information
Study not scientifically justified due to lack of human exposure.
Justification for classification or non-classification
There are no data available on potential developmental or reproduction toxicity and no classification is proposed.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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