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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

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Administrative data

Link to relevant study record(s)

Description of key information

Toxicity to predators via secondary poisoning is not expected for Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates

Key value for chemical safety assessment

Additional information

No avian toxicity data are available for Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates (CAS No. 97593-30-1). According to Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.6.1, any need for testing for this endpoint should be carefully considered taking into account the large mammalian dataset that is usually available at this tonnage level.

Glycerides, C8-21 and C8-21-unsaturated, mono- and di-, acetates is the substance is not toxic to mammals (not classified for toxicity). The substance is readily biodegradable with a low potential for bioaccumulation in biota and therefore, according to the Guidance on information requirements and chemical safety assessment, Chapter R.7c, secondary poisoning is unlikely to occur (ECHA, 2008). Due to the metabolization via enzymatic hydrolysis of the Glycerides category members, a relevant uptake and bioaccumulation in biota is not expected. Enzymatic breakdown will initially lead to the free fatty acid and glycerol (and for this substance additionally acetic acid). Glycerides are naturally stored by organisms as long-term energy reserves. Especially in periods in which the energy demand is high (reproduction, migration, etc.), glycerides are mobilized from the storage sites as source of fatty acids. Fatty acid catabolism is the most important energy source in many species, resulting in the release of acetyl CoA and NADH (throughβ-oxidation) and eventually, via the tricarboxylic cycle, the production of metabolic energy in the form of ATP. In addition, acetic acid is naturally present in living organisms. The combination of its ionized form (acetate) with coenzyme A (CoA) plays a major role as intermediate in the citric acid cycle (acetyl-CoA). Please refer to IUCLID Section 5.3.1 for a detailed overview on bioaccumulation of the Glycerides category members.

Based on the above information and considering animal welfare, toxicity testing on birds is not deemed necessary.