Registration Dossier
Registration Dossier
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EC number: 236-537-4 | CAS number: 13423-15-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48 hour LC50: 1742 mg/L, based on read-across to Tetrahydrofuran and a 2-fold safety factor
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 742 mg/L
Additional information
There are no measured data available on the acute toxicity of Tetrahydro-3-methlyfuran to aquatic invertebrates. However, testing on a closely related analog substance, Tetrahydrofuran (CAS# 109-99-9), has been performed with Daphnia magna according to a protocol equivalent or similar to OECD 202 guideline method under static conditions yielding a 48 hour LC50 value of 3485 mg/L (DuPont, 1980) and according to DIN 38412, part 11, under static conditions yielding a 24 hour EC50 (mobility) of 5930 mg/L (Bringmann, 1982). Applying a safety factor of 2 as suggested in the justification for read across document yields an LC50 value of 1742 mg/L, suggesting a low degree of acute toxicity to aquatic invertebrates.
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