Registration Dossier

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Administrative data

Key value for chemical safety assessment

Additional information


Gene mutation in bacteria

In the key study according to OECD TG 471 and GLP, isopulegol was not mutagenic with and without metabolic activation when tested up to 5000 μg/plate using Salmonella typhimurium TA 1535, TA 100, TA 1537, TA 98 and E. coli WP2 uvrA (BASF2010; 40M0358/10M055).

Short description of key information:
In-vitro Gene mutation in bacteria (AMES acc. to OECD TG 471, GLP): negative (BASF2010; 40M0358/10M055).

Endpoint Conclusion:

Justification for classification or non-classification

The present data on genetic toxicity do not fulfill the criteria laid down in 67/548/EEC and regulation (EU) 1272/2008 and therefore, a non-classification is warranted.