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Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Endpoint:
toxicity to soil macroorganisms except arthropods: short-term
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
review article or handbook
Title:
Determination of the toxicity of DHTDMAC to the earthworm Eisenia foetida, BIOD/82/06
Author:
Coulson et al
Year:
1989
Bibliographic source:
ECETOC Technical Report No. 53, DHTDMAC Aquatic & terrestrial Hazard Assessment

Materials and methods

Principles of method if other than guideline:
no details on guideline given
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides
EC Number:
263-090-2
EC Name:
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides
Cas Number:
61789-80-8
Molecular formula:
R2Me2N(+)Cl(-) whereas R = mainly C16, 18-alkyl molecular weight range is based on R=14 (lower limit value) and R=18 (higher limit value)
IUPAC Name:
N,N-Dimethyl-N,N-di-n-alkyl(C16-18)-ammoniumchloride
Test material form:
liquid
Details on test material:
100 % active ingredient (solid) dissolved in methanol, i.e. product (solution in methanol) with 76.1% active ingredient

Study design

Study type:
laboratory study
Substrate type:
artificial soil
Limit test:
yes
Total exposure duration:
14 d

Test conditions

Details on test conditions:
no details given

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
NOEC
Effect conc.:
1 000 mg/kg soil dw
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: mortality, behavioural effects, loss of bodyweight

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
based on assessment within EU RAR on DODMAC (2009)
Conclusions:
The toxicity of DHTDMAC to earthwom was tested over 14d at 1000 mg/kg dw. No effects were observed with respect to mortality, behaviour and loss of bodyweight.