Registration Dossier
Registration Dossier
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EC number: 215-246-6 | CAS number: 1314-87-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well-documented publication which meets basic scientific principles
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 993
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Rats wereb fed ≤38µm size particles of lead sulfide
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
Test animals
- Species:
- rat
- Strain:
- Fischer 344
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: feed
- Vehicle:
- other: mixed in diet
- Doses:
- 0, 10, 30 and 100 ppm
- No. of animals per sex per dose:
- 10 animals per dose
- Control animals:
- yes
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
- Conclusions:
- In the conditions of the studies, lead sulfide did not induce toxic effect due to its low bioavailability.
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