Registration Dossier
Registration Dossier
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EC number: 209-132-5 | CAS number: 556-61-6
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Summary of toxicity data on methyl isothiocyanate (MITC)
- Author:
- Anonymous
- Year:
- 1 990
- Bibliographic source:
- Nippon Noyaku Gakkai (J. Pesticide Sci.), 15(2), 297-304.
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyl isothiocyanate
- EC Number:
- 209-132-5
- EC Name:
- Methyl isothiocyanate
- Cas Number:
- 556-61-6
- Molecular formula:
- C2H3NS
- IUPAC Name:
- isothiocyanatomethane
- Details on test material:
- no data
Constituent 1
Test animals
- Species:
- other: rat and mouse
- Strain:
- not specified
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- no data
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- not specified
- Details on exposure:
- no
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Details on study design:
- no
- Statistics:
- no data
Results and discussion
Effect levelsopen allclose all
- Sex:
- male
- Dose descriptor:
- LC50
- Effect level:
- 60 mg/kg bw
- Remarks on result:
- other: RATS
- Sex:
- female
- Dose descriptor:
- LC50
- Effect level:
- 59 mg/kg bw
- Remarks on result:
- other: RATS
- Sex:
- male
- Dose descriptor:
- LC50
- Effect level:
- 75 mg/kg bw
- Remarks on result:
- other: MICE
- Sex:
- female
- Dose descriptor:
- LC50
- Effect level:
- 89 mg/kg bw
- Remarks on result:
- other: MICE
- Mortality:
- LD50 were determined.
- Clinical signs:
- no data
- Body weight:
- no data
- Gross pathology:
- no data
- Other findings:
- no data
Applicant's summary and conclusion
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