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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Description of key information

Distribution coefficients (Log D) at 20 deg C:

log D = - 1.16 at pH= 2.0 (stomach)

log D = - 3.53 at pH= 5.5 (skin)

log D = - 6.09 at pH= 7.4 (plasma)

log D = - 6.14 at pH= 8.0 (river)

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

Databases of experimental values report a log10 Pow of malic acid as being - 1.26, typical of the undissociated form.


In case of human and environmental assessment, because we need to consider all the charge-state forms of malic acid dissolved in water and in octanol, the log D (distribution coefficients) were estimated taking account for the pH dependence of the substance in aqueous solution.