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EC number: 230-022-8
CAS number: 6915-15-7
Individual and average redness (R) and swelling (S) values
Dermal application of 0.5 g fumaric acid was mildly irritating to the
skin of male and female rabbits. Fumaric acid did not elicit dermal
reactions that would exceed the threshold for classification in
accordance with EU criteria.
Read across to fumaric acid is considered valid and malic acid is
considered to exhibit similar properties. Classification is not required
The rational for read across is that fumaric acid will metabolise in
biological systems to malic acid.
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