Registration Dossier
Registration Dossier
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EC number: 449-400-0 | CAS number: 25822-43-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The performance of a test for long-term toxicity to fish was considered scientifically not justified.
REACH Regulation (EC) No 1907/2006, Annex VIII, Sect. 9.1.3, Col. 2, states as follows: 9.1.3: The study (long-term toxicity to fish) does not need to be conducted if:
- there are mitigating factors indicating that aquatic toxicity is unlikely to occur, for instance if the substance is highly insoluble in water or the substance is unlikely to cross biological membranes”
The test item is practically insoluble in aquatic environment. In addition, based on the high Log Pow of 9.2, the substance is very unlikely to pass biological membranes. The substance is not toxic to all 3 trophic levels in acute tests. Therefore, the substance is not expected to be toxic in chronic tests. Thus, the CSR does not show a need for an additional long-term aquatic test. Risk assessment is based on the short-term tests for all trophic levels.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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