Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: 4e: Documentation insufficient for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
No information
Author:
Marhold, J.
Year:
1986
Bibliographic source:
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, Pg. 1071,1986

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Standard Draize test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorobenzenesulphonyl chloride
EC Number:
202-685-3
EC Name:
4-chlorobenzenesulphonyl chloride
Cas Number:
98-60-2
Molecular formula:
C6H4Cl2O2S
IUPAC Name:
4-chlorobenzenesulphonyl chloride

Test animals / tissue source

Species:
rabbit

Test system

Duration of treatment / exposure:
DOSE/DURATION : 50 µg/24h
Details on study design:
Administration into the eye

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: severely irritant
Conclusions:
The substance is a severe eye irritant.