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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
bioaccumulation in aquatic species, other
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bioaccumulation aquatic/ sediment by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2013
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
Data is from PBT Profiler .
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
5-aminonaphthalene-2-sulphonic acid
EC Number:
204-351-2
EC Name:
5-aminonaphthalene-2-sulphonic acid
Cas Number:
119-79-9
Molecular formula:
C10H9NO3S
IUPAC Name:
5-aminonaphthalene-2-sulfonic acid
Details on test material:
Name of the test material: 5-aminonaphthalene-2-sulphonic acid
Molecular formula: C10H9NO3S
Molecular weight: 223.26
Physical state: Solid
Substance Type: Organic
Radiolabelling:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: Fish

Study design

Route of exposure:
aqueous
Test type:
other: Estimation
Water / sediment media type:
not specified

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
3.2
Calculation basis:
other: Estimation

Applicant's summary and conclusion

Conclusions:
The estimated bioconcentration factor (BCF) for 5-aminonaphthalene-2-sulphonic acid is 3.2 which does not exceed the bioconcentration threshold of 2000. Thus, it is concluded that 5-aminonaphthalene-2-sulphonic acid is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Executive summary:

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).

The estimated BCF of the key study was obtained to be 3.2. This low value of BCF of 5-aminonaphthalene-2-sulphonic acid indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.