Registration Dossier
Registration Dossier
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EC number: 228-503-2 | CAS number: 6283-86-9
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
2-ethylhexyl lactate, as all lactate esters, is rapidly hydrolyzed in-vivo into lactic acid and 2-ethylhexanol (see 7.9.3.001).
Lactic acid is a ubiquitous and essential biological molecule, in humans and other mammals, but also in most if not all vertebrate and invertebrate animals, as well as in many micro-organisms. As such the biokinetics, metabolism and distribution of lactic acid have to be considered in the context of its normal biochemistry; exogenous lactic acid will be indistinguishable from endogenous lactic acid and will follow the same biochemical pathways as endogenous lactic acid, at least up to a certain systemic level.
The biochemistry of lactic acid has been reviewed and summarized in Sterenborg, 2007 (see the lactic acid registration dossier).
2-ethylhexanol is an alcohol that is metabolized by the normal alcohol metabolism pathways.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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