Registration Dossier
Registration Dossier
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EC number: 203-874-3 | CAS number: 111-48-8
Guidance on Safe Use
Administrative data
First-aid measures
4.1. Description of first aid measures
Remove contaminated clothing.
If inhaled:
Keep patient calm, remove to fresh air, seek medical attention. Immediately administer a corticosteroid from a controlled/metered dose inhaler.
On skin contact:
Immediately wash thoroughly with plenty of water, apply sterile dressings, consult a skin specialist.
On contact with eyes:
Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open, consult an eye specialist.
On ingestion:
Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms: The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11.
4.3. Indication of any immediate medical attention and special treatment needed
Treatment: Treat according to symptoms (decontamination, vital functions), no known specific antidote.
Fire-fighting measures
5.1. Extinguishing media
Suitable extinguishing media:
water spray, dry powder, foam, carbon dioxide
5.2. Special hazards arising from the substance or mixture
sulphur dioxide
The substances/groups of substances mentioned can be released in case of fire.
5.3. Advice for fire-fighters
Special protective equipment:
Wear a self-contained breathing apparatus.
Further information:
The degree of risk is governed by the burning substance and the fire conditions. Contaminated extinguishing water must be disposed of in accordance with official regulations.
Accidental release measures
6.1. Personal precautions, protective equipment and emergency procedures
Personal protection: wear a tightly closed chemical protection suit and a self-contained breathing apparatus.
6.2. Environmental precautions
Do not discharge into drains/surface waters/groundwater. Contain contaminated water/firefighting water. Discharge into the environment must be avoided.
6.3. Methods and material for containment and cleaning up
For large amounts: Pump off product.
For residues: Pick up with suitable absorbent material (e.g. sand, sawdust, general-purpose binder, kieselguhr). Dispose of absorbed material in accordance with regulations.
6.4. Reference to other sections
Information regarding exposure controls/personal protection and disposal considerations can be found in section 8 and 13.
Handling and storage
7.1. Precautions for safe handling
Ensure thorough ventilation of stores and work areas.
Protection against fire and explosion:
No special precautions necessary.
7.2. Conditions for safe storage, including any incompatibilities
Do not store with: hydrochloric acid...%
Further information on storage conditions: Keep container tightly closed. Keep in a cool place. Protect against moisture.
7.3. Specific end use(s)
For the relevant identified use(s) listed in Section 1 the advice mentioned in this section 7 is to be observed.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
8.1. Control parameters
Components with occupational exposure limits
60-24-2: 2-Mercaptoethanol
8.2. Exposure controls
Personal protective equipment
Respiratory protection:
Respiratory protection in case of vapour/aerosol release. Gas filter for gases/vapours of organic compounds (boiling point >65 °C, e. g. EN 14387 Type A)
Hand protection:
Suitable materials also with prolonged, direct contact (Recommended: Protective index 6, corresponding > 480 minutes of permeation time according to EN 374):
fluoroelastomer (FKM) - 0.7 mm coating thickness
butyl rubber (butyl) - 0.7 mm coating thickness
Suitable materials short-term contact and/or splashes (recommended: At least protective index 2, corresponding > 30 minutes of permeation time according to EN 374)
nitrile rubber (NBR) - 0.4 mm coating thickness
chloroprene rubber (CR) - 0.5 mm coating thickness
Supplementary note: The specifications are based on tests, literature data and information of glove manufacturers or are derived from similar substances by analogy. Due to many conditions (e.g. temperature) it must be considered, that the practical usage of a chemical-protective glove in practice may be much shorter than the permeation time determined through testing.
Manufacturer's directions for use should be observed because of great diversity of types.
Eye protection:
Safety glasses with side-shields (frame goggles) (f.e. EN 166) and face shield
Body protection:
Body protection must be chosen depending on activity and possible exposure, e.g. apron, protecting boots, chemical-protection suit (according to EN 14605 in case of splashes or EN ISO 13982 in case of dust).
General safety and hygiene measures
Do not inhale gases/vapours/aerosols. Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin and eyes. Take off immediately all contaminated clothing.
Stability and reactivity
10.1. Reactivity
Formation of flammable gases: Remarks: Forms no flammable gases in the presence of water.
10.2. Chemical stability
The product is stable if stored and handled as prescribed/indicated.
10.3. Possibility of hazardous reactions
Reacts with acids and strong oxidizing agents. Reacts with acid chlorides. Reacts with peroxides. Contact with acids liberates toxic gases.
10.4. Conditions to avoid
Avoid prolonged exposure to extreme heat. Avoid humidity.
10.5. Incompatible materials
Substances to avoid:
hydrochloric acid...%, acids, oxidizing agents, strong bases
10.6. Hazardous decomposition products
Hazardous decomposition products:
hydrogen sulphide, Epithioethane
sulfides, sulfur oxides, sulphur compounds
Disposal considerations
13.1. Waste treatment methods
Incinerate in suitable incineration plant, observing local authority regulations.
Contaminated packaging:
Uncontaminated packaging can be re-used.
Packs that cannot be cleaned should be disposed of in the same manner as the contents.
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