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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Description of key information

According to QSAR prediction data , the 72 h value of difluoroacetic acid on Green algae is estimated to be NOEC: 106.73 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
106 mg/L

Additional information

No. of studies reviewed for short – term toxicity to aquatic algae and cyanobacteria from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below



Sr. No.


Effect values

Basis for effects






106.73 mg/L


72 hrs

Pseudokirchneriella subcapitata

Predicted data from QSAR



4141.50 mg/L


96 hrs

Green Algae

Predicted data from ECOSAR


By applying weight of evidence approach to the test substance difluoroacetic acid, the endpoint value was found to NOEC = 106.73 mg/L at 72 Hrs & LC50 at 4141.50 mg/L in a 96 hrs. at 72 hrs. study on the basis of growth effect. The BCF value of difluoroacetic acid reported was not >= 500 as well as the substance was found to be rapidly degradable