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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

According to QSAR prediction data , the 72 h value of difluoroacetic acid on Green algae is estimated to be NOEC: 106.73 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
106 mg/L

Additional information

No. of studies reviewed for short – term toxicity to aquatic algae and cyanobacteria from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below



Sr. No.


Effect values

Basis for effects






106.73 mg/L


72 hrs

Pseudokirchneriella subcapitata

Predicted data from QSAR



4141.50 mg/L


96 hrs

Green Algae

Predicted data from ECOSAR


By applying weight of evidence approach to the test substance difluoroacetic acid, the endpoint value was found to NOEC = 106.73 mg/L at 72 Hrs & LC50 at 4141.50 mg/L in a 96 hrs. at 72 hrs. study on the basis of growth effect. The BCF value of difluoroacetic acid reported was not >= 500 as well as the substance was found to be rapidly degradable