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Ecotoxicological information

Toxicity to birds

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Description of key information

No biologically effects could be observed in birds up to the highest test concentration of the test substance. 

Key value for chemical safety assessment

Additional information

After single oral application LD50 values of >2000 mg /kg bw were obtained in a study with northern bobwhite quails (Barfknecht, 2004). Neither mortality nor clinical signs of toxicity occurred in the study. Short-term (5-day) feeding resulted in LC50 values of > 4542 and> 4959ppm (diet, measured data) for mallard duck and northern bobwhite quail (Stoughton 2004, 2004 and 2006). Neither mortality nor clinical signs of intoxication attributable to the test substance were observed in any study. In two reproduction studies (Stoughton, 2007 and Temple, 2006) one conducted with the northern bobwhite quail and the other one with the mallard duck, the NOAEL for systemic and reproductive toxicity was considered to be > 1100 ppm (diet), which is the maximal dose according to the OECD testing guideline.

The substance showed no acute, short- and long-term hazard potential to birds as evidenced by endpoint data being above or equal the limit doses as specified in the corresponding testing guidelines. All studies referred to herein have been conducted according to the prevailing OECD or US EPA testing guidelines and GLP.