Registration Dossier
Registration Dossier
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EC number: 229-654-7 | CAS number: 6640-24-0
Respiratory sensitisation
Administrative data
- Endpoint:
- respiratory sensitisation
- Remarks:
- other: In silico prediction
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- In silico prediction. DEREK is a knowledge-based expert system designed to apply structure-activity relationships to compounds for which little or no data exists and hence to aid in the assessment of their potential toxicity. The DEREK knowledge base contains a large number of rules that associate a chemical structure with one or more toxicity end points. When a structural alert is identified a reasoning programme assigns a probability to the expression of toxicity by the test compound.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-(m-chlorophenyl)piperazine
- EC Number:
- 229-654-7
- EC Name:
- 1-(m-chlorophenyl)piperazine
- Cas Number:
- 6640-24-0
- Molecular formula:
- C10H13ClN2
- IUPAC Name:
- 1-(3-chlorophenyl)piperazine
Constituent 1
Results and discussion
- Results:
- DEREK evaluation showed no alert for respiratory sensitisation.
Applicant's summary and conclusion
- Interpretation of results:
- other: no alert
- Conclusions:
- DEREK evaluation showed no alert for respiratory sensitisation.
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