Registration Dossier
Registration Dossier
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EC number: 201-756-6 | CAS number: 87-60-5
Endpoint summary
Administrative data
Description of key information
The studies on oral toxicity are reliable. For dermal exposure there are only very old datas with doubtable reliability available. Since there are several hints that the substance can be resorbed percutaneous and enteral and because it is known that the substance causes cyanosis a precautionary classification as harmful in contact with skin is justified.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 681 mg/kg bw
Additional information
Justification for classification or non-classification
There are reliable studies on oral toxicity. Studies on dermal and subcutaneous toxicity are very old and because of this not very reliable. Nevertheless this results combined with fact that chlortoluidines can be absorbed through the skin and cause cyanosis (like anilines) a classification as harmful if swallowed and in contact to skin can be justified.
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