2-amino-2-methylpropanol

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

Not applicable

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference 1

Reference Type:

study report

Title:

Unnamed

Year:

1992

Reference 2

Reference Type:

study report

Title:

Unnamed

Year:

1989

Report date:

1989

Materials and methods

Principles of method if other than guideline:

screening BCF over 3 days

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-amino-2-methylpropanol

EC Number:

204-709-8

EC Name:

2-amino-2-methylpropanol

Cas Number:

124-68-5

Molecular formula:

C4H11NO

IUPAC Name:

2-amino-2-methylpropan-1-ol

Specific details on test material used for the study:

Details on properties of test surrogate or analogue material (migrated information):
Not applicable

Radiolabelling:

yes

Test solutions

Vehicle:

yes

Details on preparation of test solutions, spiked fish food or sediment:

14-C-labeled chemical was dissolved in the water at a concentration of 50ppb

Test organisms

Test organisms (species):

Leuciscus idus

Study design

Route of exposure:

aqueous

Test type:

static

Water / sediment media type:

natural water: freshwater

Total exposure / uptake duration:

3 d

Test conditions

Details on test conditions:

Five Gold orfes were raised in a test vessel with 8L of water, in which the 14-C-labeled chemical was dissolved at a concentration of 50ppb. The fish were not fed during the 3-day test. The vessel was closed and the water surface was stirred with a blade stirrer gently to provide air exchange and movement of water.

Details on estimation of bioconcentration:

At the end of the experiment, the concentration of AMP was determined by measuring the radioactivity of the fish and in the water and, from that, the accumulation factor was determined.

Results and discussion

Bioaccumulation factor

Type:

BCF

Value:

< 1

Remarks on result:

other: no bioaccumulation

Remarks:

Conc.in environment / dose:50 ppb