Registration Dossier

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13.08.2012-04.09.2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: study report
Justification for type of information:
Data is from experimental study report
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium.
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water
Analytical method:
not specified
Type:
Pow
Partition coefficient:
0.2
Temp.:
30 °C
pH:
6.44
Details on results:
Converting the above Pow value into its Log value, the Log Pow of test chemical is -0.698 at temperature 30 degC and pH of 6.44.
Conclusions:
The experimental value of octanol water partition co-efficient (log Pow) of test chemical is -0.698 at 30 degC and pH of 6.44.This value indicates that the substance is hydrophilic in nature.
Executive summary:

The experimental value of octanol water partition co-efficient (log Pow) of test chemical is -0.698 at 30 degC and pH of 6.44.This value indicates that the substance is hydrophilic in nature.

Description of key information

The experimental value of octanol water partition co-efficient (log Pow) of test chemical is -0.698 at 30 degC and pH of 6.44.This value indicates that the substance is hydrophilic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.698
at the temperature of:
25 °C

Additional information

Following studies have been conducted to determine log Pow of test chemical.

In first study the experimental value of octanol water partition co-efficient (log Pow) of test chemical is -0.698 at 30 degC and pH of 6.44.

In another study the experimental value of octanol water partition co-efficient (log Pow) of test chemical is -0.958 at 30 degC and pH of 4.50.

These log Pow values indicate that the substance is hydrophilic in nature.