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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
experimental data for various test chemicals
Justification for type of information:
experimental data for various test chemicals
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
other: Refer the principle below
Principles of method if other than guideline:
WoE report is prepared based on toxicity to green algae study:
2 and 3
GLP compliance:
no
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
other: 3. Scenedesmus subspicatus 4. Scenedesmus quadricauda
Test type:
static
Water media type:
freshwater
Total exposure duration:
96 h
Remarks on exposure duration:
for 3rd study period was 8 days.
Reference substance (positive control):
not specified
Duration:
8 d
Dose descriptor:
EC50
Effect conc.:
1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: From study 3
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: From Study report 2
Validity criteria fulfilled:
not specified
Conclusions:
The effect of test chemical was studied on the green algae the effective concentration range was determined to be 100 -1000 mg/L.
Executive summary:

Short term toxicty for the test chemical are studied and mention as below:

The short-term toxicity of the test substance to green algae is studied using the RA , This study outlines the effect of test chemical on the Scenedesmus subspicatus. The study was performed on the in accordance with OECD guideline 201. The test was performed for the period 96 hours to observe the effects. Based on the results obtained the EC50 value was determined to >100 mg/L. According to the CLP classification the test chemical cannot be classified.

Similar study outlines the effect of test chemical on the Scenedesmus quadricauda. The test was performed for the period 8 days to observe the effects.

Based on the results obtained the 8d- EC50 value was determined to 1000mg/l. According to the CLP classification the test chemical is not classified.

Thus the toxicity is ranging from 100 to 1000mg/L

Description of key information

The short-term toxicity of the test substance to green algae is studied using the RA, This study outlines the effect of test chemical on the Scenedesmus subspicatus. The study was performed on the in accordance with OECD guideline 201. The test was performed for the period 96 hours to observe the effects.

Based on the results obtained the EC50 value was determined to >100 mg/L. According to the CLP classification the test chemical cannot be classified.

Key value for chemical safety assessment

EC50 for freshwater algae:
100 mg/L

Additional information

Short term toxicity for the test chemical and structurally and functionally similar read across chemical are studied and mention as below:

 

The short-term toxicity of the test substance to green algae is studied using the RA, This study outlines the effect of test chemical on the Scenedesmus subspicatus. The study was performed on the in accordance with OECD guideline 201. The test was performed for the period 96 hours to observe the effects. Based on the results obtained the EC50 value was determined to >100 mg/L. According to the CLP classification the test chemical cannot be classified.

 

Similar study outlines the effect of test chemical on the Scenedesmus quadricauda. The test was performed for the period 8 days to observe the effects.

Based on the results obtained the 8d- EC50 value was determined to 1000mg/l.

According to the CLP classification the test chemical is not classified.

 

Thus the toxicity is ranging from 100 to 1000mg/L.