Registration Dossier
Registration Dossier
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EC number: 200-543-5 | CAS number: 62-56-6
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- January 2003
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- GLP compliance:
- not specified
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- >= 164 - <= 178 °C
- Atm. press.:
- ca. 101 325 Pa
- Decomposition:
- no
- Sublimation:
- no
- Conclusions:
- The melting point of Thiourea is 178.3 °C.
- Executive summary:
The melting point of Thiourea was determined applying differential scanning calorimetry (DSC). The test protocol is equivalent to the guideline EU A.01. The test substance, 6.9 mg Thiourea, were put into a platen at room temperature and heated up to approximately 400°C. The onset and the peak of the endothermic heat fluxes were reported. The onset of the endothermic heat flux is 163.7 °C and reaches a peak at 178.3 °C. According the guideline EU A.01 the melting point is the temperature at which the final stage of melting is reached. Therefore, the melting point of Thiourea is 178.3 °C.
Reference
The melting point of Thiourea was determined applying DSC. 6.9 mg test substance were put into a platen and heated up to approximetaly 400°C. The onset (163.7 °C) and the peak (178.3 °C) of the endothermic heat fluxes were measured. The melting point is reported as the peak of the endothermic heat fluxes.
Description of key information
The melting point of Thiourea determined by differential scanning calorimetry is 178.3 °C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 178 °C
Additional information
According the Ullmann`s Encyclopedia of Industrial Chemistry Thiourea has no sharp melting point, as it rearranges relatively rapidly to NH4SCN from 135°C; on rapid heating a melting point of 180°C has been determined. According the CRC Handbook for Chemistry and Physics the melting point of Thiourea is ca.176°C.
The melting point of Thiourea determined by differential scanning calorimetry (DSC) is 178.3 °C. As this value represents the only direct experimental result and is considered reliable, this value is carried forward in the risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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