Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-924-1 | CAS number: 68391-05-9 This substance is identified by SDA Substance Name: C12-C18 dialkyl dimethyl ammonium chloride and SDA Reporting Number: 16-047-00.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in soil: simulation testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Transformation products:
- not specified
- Remarks:
- Refer to the endpoint summary
Reference
Description of key information
The available soil biodegradation studies with the read across substances indicated that around 18-60% mineralisation was observed within 120-430 days. Therefore, a half-life of 500 days was concluded in the EU RAR report for the purpose of risk assessment. Based on read across approach, a similar half-life can be assumed for the test substance.
Key value for chemical safety assessment
- Half-life in soil:
- 500 d
Additional information
No soil biodegradation study could be located on C12 -18 DAQ. Therefore, literature evidence on read across substances (C16-18 DAQ and C18 DAQ), which has been exhaustively reviewed in the frame of a European Risk Assessment (RAR) published in 2002 by German Authorities. Both the test and read across substances are di-alkyl dimethyl ammonium chloride compounds. C18 DAQ or C16-DAQ is structurally the same but only differs in containing a longer average alkyl chain length. Longer alkyl chains are expected to be less bioavailable which likely results in lower biodegradation rates. Using the available biodegradation and half-life results available for C16-18 (and C18) DAQ for read-across to C12-18 DAQ is therefore considered as a worst-case approach (Refer to the read across justification for details).
An overview of the soil biodegradation studies from the EU RAR report have been presented below:
Degradation of 14C-C18 DAQ(CAS 107-64 -2) in sandy loam and loam mixed with digested sewage sludge was measured with a batch incubated flask method (Fieler, 1975a). The 14CO2-production was approximately 48% after 55 weeks in both soils, when 50 mg C18 DAQ per kg dry soil were applied. Addition of 30 mg/L LAS reduced the 14CO2production to 38% indicating complexation of the anionic LAS with the cationic DAQ. Degradation of 0.5 mg C18 DAQ/kg dry soil was measured in loam soil amended with or without digested sewage sludge and two other soils. The 14CO2-production after 62 weeks was as follows: ca. 27% in sandy loam and loam with sludge; ca. 18% in loam without sludge and silt loam. At concentrations of 5 and 50 mg/kg C18 DAQ degradation increased in all soils with highest results of 50 and 63% in sludge amended soils.
Degradation ofC18 DAQin soils over a long period of 116 days was reported also from other tests (Weston, 1987). 0.1 mg C18 DAQ/kg dry soil was degraded to 18-27% based on 14CO2-production and at 1.0 mg/kg degradation was 34-38%.
A comparable degradation test withC16-18 DAQ(CAS 92129-33-4) lasted 120 days (Weston, 1989). In sandy loam with sludge 0.1 mg C16-18 DAQ/kg dry soil showed 36 and 52% 14CO2-production. Corresponding values of 38 and 41% were derived with 1.0 mg/kg under the same conditions.
Procter & Gamble (1992, unpublished study, cited in ECETOC 1993.) performed various studies on the biological degradation ofC18 DAQin soils using several types of dispersion of the substance. Aqueous dispersion resulted in about 35% 14CO2-production after a mean test period of 118 days. The mean degradation of C16-18 DAQ as a solution with a solvent was below 15% after a mean test period of 184 days. In these cases, the majority of the test results were obtained between 130 and 169 days where the 14CO2-production was less than 10%. Degradation results for C16-18 DAQ in lecithin emulsions were in between.
In a 72-day study, no degradation of 14C-C16-18 DAQcould be observed under anaerobic conditions (Fieler, 1975b). No other study could find any evidence that C16-18 DAQ undergoes anaerobic degradation.
Overall, the available soil biodegradation studies with the read across substances indicated that around 18-60% mineralisation occurred within 120-430 days. Therefore, a half-life of 500 days was concluded in the EU RAR report for the purpose of risk assessment. Based on read across approach, a similar half-life can be assumed for the test substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
