Registration Dossier
Registration Dossier
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EC number: 236-948-9 | CAS number: 13560-89-9
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- The method of calculation is not specified
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Estimation of first-order rate constant, method of calculation not specified.
- GLP compliance:
- no
- Radiolabelling:
- no
- Analytical monitoring:
- not required
- Buffers:
- none
- Estimation method (if used):
- not specified
- Details on test conditions:
- no test
- Number of replicates:
- none
- Positive controls:
- no
- Negative controls:
- no
- Statistical methods:
- not specified
- Transformation products:
- not specified
- Details on hydrolysis and appearance of transformation product(s):
- No details reported
- Details on results:
- The first-order rat constant for the oxidation of Dechlorane Plus in water was estimated to be 1/10000000000 / sec corresponding to an oxidation half-life in water of 2100 years.
- Validity criteria fulfilled:
- no
- Conclusions:
- No valid results, as the method of estimation and calculation was not described.
- Executive summary:
The rate of oxidation of Dechlorane Plus in water was estimated as first-order rate constant with 1/10000000000 / sec corresponding to an oxidation half-life in water of 2100 years. The method of estimation and calculation was not reported.
- Endpoint:
- hydrolysis
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is highly insoluble in water
Referenceopen allclose all
Description of key information
In accordance with column 2 of REACH Annex VIII, section 9.2.2.1, the study does not need to be conducted for substances highly insoluble in water.
Key value for chemical safety assessment
Additional information
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