Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 294-620-0 | CAS number: 91744-56-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC = 45.5 mg/L (from ready biodegradation test, 78.7% biodegradation in toxicity control within 14 days)
Key value for chemical safety assessment
Additional information
No standard studies evaluating the effect of Glycerides, mixed C8-10 and succinyl (CAS No. 91744-56-8) on respiration inhibition of aquatic microorganisms are available. Therefore, a ready biodegradability study is used to derive a NOEC for this endpoint. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment, Chapter R.7b (ECHA 2012).
A substance can be assumed to be not inhibitory of the activity of aquatic microorganisms if, in the toxicity control of a ready biodegradation test, more than 25% biodegradation occurs within a period of 14 days (OECD Guideline 301). For Glycerides, mixed C8-10 and succinyl, a biodegradation screening test according to OECD 301B is available (Flach, 2012). This test includes a toxicity control containing 45.5 mg/L of test material. Within 14 days, 78.7% biodegradation took place in this toxicity control clearly indicating the lack of toxic potential of Glycerides, mixed C8-10 and succinyl to activated sludge microorganisms, and therefore, the test item concentration of 45.5 mg/L can be used as a NOEC value.
Based on the above information it is considered that Glycerides, mixed C8-10 and succinyl is not inhibitory of microorganisms’ activity and further testing for this endpoint is not deemed necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
