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EC number: 203-842-9 | CAS number: 111-18-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21-day EC10 for daphnia reproduction was found to be 0.86 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.86 mg/L
Additional information
The long-term toxicity of N,N,N',N'-Tetramethylhexamethylenediamine (CAS 111 -18 -2) was assessed in an OECD 211 reproduction test (under GLP) using Daphnia magnaas test organism (BASF SE 2013, report no. 51E0487/11E119). Daphnia were exposed to the test substance at nominal concentrations ranging from 0.10 to 4.6 mg/L. Parent mortality, abnormal effects and numbers of live and dead offspring were assessed every day. Test concentration analyses was carried out by HPLC.
The 21 -day NOEC for reproduction was found to be 1.0 mg/L and the EC10 was 0.86 mg/L. The 21 -day NOEC for mortality was 2.2 mg/L and the EC10 3.03 mg/L. The results are based on analytically verified time-weighted average concentrations, the pH in the test solutions was not adjusted.
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