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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The 21-day EC10 for daphnia reproduction was found to be 0.86 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.86 mg/L

Additional information

The long-term toxicity of N,N,N',N'-Tetramethylhexamethylenediamine (CAS 111 -18 -2) was assessed in an OECD 211 reproduction test (under GLP) using Daphnia magnaas test organism (BASF SE 2013, report no. 51E0487/11E119). Daphnia were exposed to the test substance at nominal concentrations ranging from 0.10 to 4.6 mg/L. Parent mortality, abnormal effects and numbers of live and dead offspring were assessed every day. Test concentration analyses was carried out by HPLC.

The 21 -day NOEC for reproduction was found to be 1.0 mg/L and the EC10 was 0.86 mg/L. The 21 -day NOEC for mortality was 2.2 mg/L and the EC10 3.03 mg/L. The results are based on analytically verified time-weighted average concentrations, the pH in the test solutions was not adjusted.