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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

With high probability acutely not harmful to algae

Key value for chemical safety assessment

EC50 for freshwater algae:
155 mg/L
EC10 or NOEC for freshwater algae:
13.5 mg/L

Additional information

A study was performed according to OECD 201 under GLP conditions regarding the toxic effect of N,N,N´,N´-Tetramethyl-1,6-hexanediamine (CAS 111 -18 -2) towards algae (BASF SE, 2012; report no. 60E0487/11E118). The test species was Pseudokirchneriella subcapitata. The test concentrations were analytically verified. In inoculated samples the measured concentrations were 53 to 80% of the nominal concentration at the end of exposure. Analysis of uninoculated samples from the end of exposure showed that concentrations were within ±20% of nominal concentrations. This demonstrated that the decrease was due to binding of the test substance to the algal biomass. Therefore, the concentrations were stable and the effect values were given based on the nominal concentrations. The 72 -h effect values are as follows: ErC10 = 13.5 mg/L, ErC50 155 mg/L (BASF SE, 2012; report no. 60E0487/11E118).

In conclusion, the substance is with high probability acutely not harmful to algae.