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EC number: 482-220-0 | CAS number: 848301-69-9
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Long-term toxicity to aquatic invertebrates
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Link to relevant study record(s)
Description of key information
(21d) NOELR ≥100 mg/L (D. magna)
Key value for chemical safety assessment
Additional information
An invertebrate reproduction study has been conducted with GTL Base Oil Distillates using the freshwater speciesDaphnia magna(Goodband, 2010). The test was conducted in accordance with OECD 211 and was compliant with GLP.
Daphnia magnawere exposed to water accommodated fractions (WAFs) of the test material over a range of nominal loading rates of 10, 32 and 100 mg/l for a period of 21 days under semi-static test conditions. The WAFs were prepared by stirring for 23 hour and then leaving to stand for 1 hour.
The Lowest Observed Effect Loading Rate was considered to be greater than 100 mg/l on the basis that at this loading rate, no significant differences (P³0.05) were observed between the control and the 100 mg/l WAF loading rate in terms of numbers of live young produced per adult by Day 21.
The No Observed Effect Loading Rate (NOELR) was considered to be 100 mg/l on the basis that at this loading rate there were no significant mortalities (immobilisation) observed in the parental generation (P1) and that there were no significant differences (P³0.05) between the control and the 100 mg/l loading rate WAF test group in terms of numbers of live young produced per adult by Day 21.
Total Organic Carbon (TOC) analysis of the freshly prepared test preparations showed amount of carbon present within the 10, 32 and 100 mg/l loading rate WAF test vessels to range from less than the limit of quantitation (LOQ) for the method (1.0 mg C/l) to 1.60 mg C/l. TOC analysis of the old test media showed amount of carbon present to range from less than the LOQ to 1.20 mg C/l.
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